Senior Research Associate - DMPK (SF Bay Area)

South San Francisco, CA

Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development. Our platform is built on ground-breaking research in advanced computational approaches and taps into uncharted chemical space to design new molecular structures not found in nature.

We are harnessing the power of our platform to go after previously impossible targets in an array of indications. Vilya’s ultimate goal is to solve some of the most challenging unmet medical needs that exist today.

Our Vision: Harness a revolution in technology and biology to better human health

Our Mission: Build an independent, leading biotech company founded on intelligent drug design to cure the incurable 

We are seeking a versatile, self-motivated DMPK Senior Research Associate to become an integral part in the discovery of macrocycle drug candidates. Our early-stage pharmaceutical company strives to employ the latest advances in technology to progress our ambitious drug discovery projects. A collaborative teammate seeking scientific rigor in a disruptive biotech would be well suited for this role. 

 

RESPONSIBILITIES: 

  • Contribute to automated processes and improve upon bioanalytical procedures to increase data output.
  • Perform in vitro DMPK assays- stability, drug permeability, and protein binding.
  • Troubleshoot and maintain LC-MS-MS equipment as well as robotic instrumentation.
  • Facilitate outsourcing of in vitro DMPK studies.
  • Work independently and with senior colleagues to implement novel methodologies to characterize DMPK properties of drug candidates.
  • Actively maintains ELN notebooks and related databases.
  • Contribute to establishing a DMPK laboratory within a new build.
  • Team player, working hand-in-hand with colleagues across the organization.
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PREFERRED QUALIFICATIONS:

  • BS/BA degree in biology, chemistry, or related science and 2+ years of experience in a DMPK or biology laboratory, including hands-on experience with DMPK-related technology and methodologies such as: automation and LC-MS/MS.
  • Ability to meet multiple deadlines, with a high degree of accuracy and efficiency.
  • Excellent problem-solving, analytical thinking skills.
  • Strong written and verbal communication skills.
  • Working knowledge in at least one DMPK job-relevant core competency (instrumental analysis and automation, enzymology, or cell culture).
  • Ability to work with a variety of laboratory instrumentation and related software.
  • Team player, working hand-in-hand with colleagues across the organization.

VILYA BENEFITS:

  • Opportunity to work in a disruptive startup with a talented, experienced, and growing team of dedicated individuals
  • 401(k) plan with employer matching for contributions
  • Stock options
  • Excellent medical, dental, and vision coverage
  • Open, flexible vacation policy
  • Support to attend professional conferences that are meaningful to your career growth
  • Monthly cell phone stipend
  • Commuter benefits
  • Salary Range : $80,000 - $115,000